Combinatorial Design Of Virtual Sialic Acid Analogues Against Influenza A Hemagglutinin Using Structure And Fragment Based Approaches

• Main Author: Al-Qattan, Mohammed Noor Al-Deen
• Format: Thesis
• Language: English
• Published: 2009
• Subjects: RM300-666 Drugs and their actions
• Online Access: http://eprints.usm.my/28928/1/Combinatorial_design_of_virtual_sialic_acid_analogues_against_influenza_a_hemagglutininusing_structure_and_fragment_based_approaches.pdf; http://eprints.usm.my/28928/

In this study molecular modeling techniques were used to design databases of virtual SA analogues by a single substitution at either of C2, C5 or C6 positions of SA scaffold. Dalam kajian ini, kaedah pemodelan molekul telah digunakan untuk mereka bentuk pangkalan data analog maya SA dengan pengga...