Characterisation, in-vitro and in-vivo evaluation of valproic acid-loaded nanoemulsion for improved brain bioavailability
OBJECTIVE: This study was aimed to investigate the potential of formulated valproic acid-encapsulated nanoemulsion (VANE) to improve the brain bioavailability of valproic acid (VPA). METHODS: Valproic acid-encapsulated nanoemulsions were formulated and physically characterised (osmolarity, viscosity...
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Main Authors: | Tan, Suk Fei, Kirby, Brian P., Stanslas, Johnson, Basri, Hamidon |
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Format: | Article |
Language: | English |
Published: |
John Wiley & Sons
2017
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Online Access: | http://psasir.upm.edu.my/id/eprint/61082/1/Characterisation%2C%20in-vitro%20and%20in-vivo%20evaluation%20of%20valproic%20acid-loaded%20nanoemulsion%20for%20improved%20brain%20bioavailability.pdf http://psasir.upm.edu.my/id/eprint/61082/ https://onlinelibrary.wiley.com/doi/full/10.1111/jphp.12800 |
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