In vitro antibacterial and time kill evaluation of mononuclear phosphanegold(I) dithiocarbamates

• Main Authors: Chen, Bao Jing, Jamaludin, Nazzatush Shimar, Khoo, Chai Hoon, See, Tian Hong, Sim, Jiun Horng, Cheah, Yoke Kqueen, Abdul Halim, Siti Nadiah, Seng, Hoi Ling, Tiekink, Edward R.T.
• Format: Article
• Language: English
• Published: Elsevier 2016
• Online Access: http://psasir.upm.edu.my/id/eprint/54533/1/In%20vitro%20antibacterial%20and%20time%20kill%20evaluation%20of%20mononuclear%20phosphanegold%20%28I%29%20dithiocarbamates.pdf; http://psasir.upm.edu.my/id/eprint/54533/; https://www.sciencedirect.com/science/article/pii/S0162013416302264

Four compounds, R3PAu[S2CN(CH2CH2OH)2], R = Ph (1) and cyclohexyl (2), and Et3PAuS2CNRꞌ2, Rꞌ = Rꞌ = Et (3) and Rꞌ2 = (CH2)4 (4), have been evaluated for antibacterial activity against a panel of 24 Gram positive (8) and Gram negative (16) bacteria. Based on minimum inhibitory concentration (MIC) sco...