Synthesis and in vitro bioactivity evaluation of new glucose and xylitol ester derivatives of 5- aminosalicylic acid

• Main Authors: Yousefi, Samira, Bayat, Saadi, Abdul Rahman, Mohd Basyaruddin, Ismail, Intan Safinar, Saki, Elnaz, Abdulmalek, Emilia
• Format: Article
• Language: English
• Published: Royal Society of Chemistry 2015
• Online Access: http://psasir.upm.edu.my/id/eprint/46465/1/Synthesis%20and%20in%20vitro%20bioactivity%20evaluation%20of%20new%20glucose%20and%20xylitol%20ester%20derivatives%20of%205-%20aminosalicylic%20acid.pdf; http://psasir.upm.edu.my/id/eprint/46465/; http://pubs.rsc.org/en/journals/journalissues/ra

New glucose and xylitol esters of 5-amino salicylic acid (5-ASA) were synthesized followed by evaluation of their in vitro antimicrobial, anti-cancer and anti-inflammatory activities. The results of the antimicrobial activity assessment revealed that the new final esters were more effective against...