Regioselective synthesis of 2-(bromomethyl)-5-aryl-thiophene derivatives via palladium (0) catalyzed suzuki cross-coupling reactions: as antithrombotic and haemolytically active molecules

• Main Authors: Rizwan, Komal, Zubair, Muhammad, Rasool, Nasir, Ali, Shaukat, Zahoor, Ameer Fawad, Rana, Usman Ali, Shahid, Muhammad, Zia-Ul-Haq, Muhammad, Jaafar, Hawa Z. E.
• Format: Article
• Published: Chemistry Central 2014
• Online Access: http://psasir.upm.edu.my/id/eprint/35192/; http://journal.chemistrycentral.com/content/8/1/74/abstract

BACKGROUND: It is seen that the regioselective functionalizations of halogenated heterocycles play an important role in the synthesis of several types of organic compounds. In this domain, the Suzuki-Miyaura reaction has emerged as a convenient way to build carbon-carbon bonds in synthesizing organ...