Optimization of genomic DNA shearing by sonication for next-generation sequencing library preparation
Next-generation sequencing (NGS) technologies, capable of sequencing genomic DNA and RNA at high throughput with unprecedented speed, have revolutionized genomic research as well as clinical diagnosis. DNA fragmentation is a critical step in library preparation in all NGS platforms, and determines t...
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Main Authors: | Lee, Le Jie, Abdullah, Maha |
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Format: | Article |
Published: |
Malaysian Society for Molecular Biology and Biotechnology
2014
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Online Access: | http://psasir.upm.edu.my/id/eprint/34771/ http://www.msmbb.org.my/apjmbb/html223/223b.html |
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