Optimization of genomic DNA shearing by sonication for next-generation sequencing library preparation

Next-generation sequencing (NGS) technologies, capable of sequencing genomic DNA and RNA at high throughput with unprecedented speed, have revolutionized genomic research as well as clinical diagnosis. DNA fragmentation is a critical step in library preparation in all NGS platforms, and determines t...

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Bibliographic Details
Main Authors: Lee, Le Jie, Abdullah, Maha
Format: Article
Published: Malaysian Society for Molecular Biology and Biotechnology 2014
Online Access:http://psasir.upm.edu.my/id/eprint/34771/
http://www.msmbb.org.my/apjmbb/html223/223b.html
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