Identifying common mutations in colorectal cancer using a 7-gene panel by next generation sequencing

• Main Authors: Chai, Boon Lee, Yip, Wai Kien, Mohd Dusa, Noraini, Mohtarrudin, Norhafizah, Seow, Heng Fong
• Format: Article
• Language: English
• Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2019
• Online Access: http://psasir.upm.edu.my/id/eprint/75577/1/2019100109012514_MJMHS_0054.pdf; http://psasir.upm.edu.my/id/eprint/75577/; https://medic.upm.edu.my/upload/dokumen/2019100109012514_MJMHS_0054.pdf

Introduction: Colorectal cancer (CRC) arises from the cumulative effects of genetic and epigenetic alterations. Cur-rent treatment of metastatic CRC relies on combination of chemotherapy and targeted therapies such as anti-EGFR therapies. The success of targeted therapies relies on the detection of...