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Methods and compositions for the prevention of opiate tolerance using mitragynine.

The present invention relates to methods and compositions to counter the side effects of analgesic treatments with opioids such as morphine. Provided are novel treatment regimes comprising the administration of mitragynine for the prevention, reversal and/or delay of the progression and/or developme...

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Main Authors: Fakurazi, Sharida, Baharuldin, Mohamad Taufik Hidayat, Mohd Moklas, Mohamad Aris, Ithnin, Hairuszah, Abd Rahman, Shamima
Format: Patent
Language:English
Published: 2011
Online Access:http://psasir.upm.edu.my/id/eprint/32077/
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id my.upm.eprints.32077
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spelling my.upm.eprints.320772014-10-15T07:45:22Z http://psasir.upm.edu.my/id/eprint/32077/ Methods and compositions for the prevention of opiate tolerance using mitragynine. Fakurazi, Sharida Baharuldin, Mohamad Taufik Hidayat Mohd Moklas, Mohamad Aris Ithnin, Hairuszah Abd Rahman, Shamima The present invention relates to methods and compositions to counter the side effects of analgesic treatments with opioids such as morphine. Provided are novel treatment regimes comprising the administration of mitragynine for the prevention, reversal and/or delay of the progression and/or development of a tolerance of a subject against the pharmaceutical effects of an opiate. Also comprised by the present invention are therapeutic means for the treatment of severe or chronic pain using a combination of mitragynine and opiates, as well as pharmaceutical compositions comprising the compounds of the present invention. 2011-01-14 Patent NonPeerReviewed Sharida Fakurazi (2011) Methods and compositions for the prevention of opiate tolerance using mitragynine. PI 2011700001. English
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description The present invention relates to methods and compositions to counter the side effects of analgesic treatments with opioids such as morphine. Provided are novel treatment regimes comprising the administration of mitragynine for the prevention, reversal and/or delay of the progression and/or development of a tolerance of a subject against the pharmaceutical effects of an opiate. Also comprised by the present invention are therapeutic means for the treatment of severe or chronic pain using a combination of mitragynine and opiates, as well as pharmaceutical compositions comprising the compounds of the present invention.
format Patent
author Fakurazi, Sharida
Baharuldin, Mohamad Taufik Hidayat
Mohd Moklas, Mohamad Aris
Ithnin, Hairuszah
Abd Rahman, Shamima
spellingShingle Fakurazi, Sharida
Baharuldin, Mohamad Taufik Hidayat
Mohd Moklas, Mohamad Aris
Ithnin, Hairuszah
Abd Rahman, Shamima
Methods and compositions for the prevention of opiate tolerance using mitragynine.
author_facet Fakurazi, Sharida
Baharuldin, Mohamad Taufik Hidayat
Mohd Moklas, Mohamad Aris
Ithnin, Hairuszah
Abd Rahman, Shamima
author_sort Fakurazi, Sharida
title Methods and compositions for the prevention of opiate tolerance using mitragynine.
title_short Methods and compositions for the prevention of opiate tolerance using mitragynine.
title_full Methods and compositions for the prevention of opiate tolerance using mitragynine.
title_fullStr Methods and compositions for the prevention of opiate tolerance using mitragynine.
title_full_unstemmed Methods and compositions for the prevention of opiate tolerance using mitragynine.
title_sort methods and compositions for the prevention of opiate tolerance using mitragynine.
publishDate 2011
url http://psasir.upm.edu.my/id/eprint/32077/
_version_ 1643830503009157120
score 13.18916

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