A curcumin derivative, 2,6-bis(2,5-dimethoxybenzylidene)-cyclohexanone (BDMC33) attenuates prostaglandin E2 synthesis via selective suppression of cyclooxygenase-2 in IFN-γ/LPS-stimulated macrophages..
Our preliminary screening had shown that the curcumin derivative [2,6-bis(2,5- dimethoxybenzylidene)cyclohexanone] or BDMC33 exhibited improved anti-inflammatory activity by inhibiting nitric oxide synthesis in activated macrophage cells. In this study, we further investigated the anti-inflammatory...
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Main Authors: | Lee, Ka Heng, Abas, Faridah, Mohamed Alitheen, Noorjahan Banu, Shaari, Khozirah, Lajis, Md. Nordin, Ahmad, Syahida |
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Format: | Article |
Language: | English English |
Published: |
MDPI
2011
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Online Access: | http://psasir.upm.edu.my/id/eprint/24101/1/A%20curcumin%20derivative.pdf http://psasir.upm.edu.my/id/eprint/24101/ |
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