Cytotoxicity and apoptosis effects of curcumin analogue (2E,6E)-2,6-Bis(2,3-Dimethoxybenzylidine) cyclohexanone (DMCH) on human colon cancer cells HT29 and SW620 in vitro

• Main Authors: Nurul Fattin, Che Rahim, Yazmin, Hussin, Muhammad Nazirul Mubin, Aziz, Nurul Elyani, Mohamad, Yeap, Swee Keong, Mas Jaffri, Masarudin, Rasedee, Abdullah, Akhtar, M. N., Noorjahan Banu, Alitheen
• Format: Article
• Language: English
• Published: MDPI AG 2021
• Subjects: QH426 Genetics; RC Internal medicine; T Technology (General)
• Online Access: http://umpir.ump.edu.my/id/eprint/32767/1/Cytotoxicity%20and%20apoptosis%20effects%20of%20curcumin%20analogue%20%282E%2C6E%29-2%2C6-Bis%282%2C3-Dimethoxybenzylidine%29.pdf; http://umpir.ump.edu.my/id/eprint/32767/; https://doi.org/10.3390/molecules26051261; https://doi.org/10.3390/molecules26051261

Colorectal cancer (CRC) is the third most common type of cancer worldwide and a leading cause of cancer death. According to the Malaysian National Cancer Registry Report 2012-2016, colorectal cancer was the second most common cancer in Malaysia after breast cancer. Recent treatments for colon cancer...