Genetic polymorphism and natural selection in the C-terminal 42 kDa region of merozoite surface protein-1 (MSP-1) among Plasmodium knowlesi samples from Malaysia
Background: The merozoite surface protein-1 (MSP-1) gene encodes for a leading malaria vaccine candidate antigen. However, its extensive polymorphic nature represents a major obstacle to the development of a protective vaccine. Previously, a pilot study was carried out to explore the sequence varia...
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Main Authors: | , , , , , , , , , , |
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格式: | Article |
語言: | English |
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BioMed Central Ltd
2018
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在線閱讀: | http://ir.unimas.my/id/eprint/42142/1/Genetic%20polymorphism.pdf http://ir.unimas.my/id/eprint/42142/ https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-018-3234-5 https://doi.org/10.1186/s13071-018-3234-5 |
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