Epithelial-to-mesenchymal transition (EMT) to sarcoma in recurrent lung adenosquamous carcinoma following adjuvant chemotherapy

• Main Authors: Chai, Chee-Shee, Poh, Mau Ern, Liam, Chong Kin, Mun, Kein Seong, Wong, Chee Kuan, Tan, Jiunn Liang, Loh, Thian Chee, Chin, Ka Kiat
• Format: E-Article
• Language: English
• Published: China Lung Oncology Group and John Wiley & Sons Australia, Ltd 2019
• Subjects: RC0254 Neoplasms. Tumors. Oncology (including Cancer)
• Online Access: http://ir.unimas.my/id/eprint/26259/1/Epithelial-to-mesenchymal%20transition%20%28EMT%29%20to%20sarcoma%20in%20recurrent%20lung%20adenosquamous%20-%20Copy.pdf; http://ir.unimas.my/id/eprint/26259/; https://onlinelibrary.wiley.com/doi/full/10.1111/1759-7714.13156

Adjuvant chemotherapy has long been indicated to extend survival in completely resected stage IB to IIIA non-small cell lung cancer (NSCLC). However, there is accumulating evidence that chemotherapy or chemoradiotherapy can induce epithelial-to-mesenchymal transition (EMT) in disseminated or circula...