Real-world experience of first-line afatinib in patients with EGFR-mutant advanced NSCLC: a multicenter observational study

• Main Authors: Chai, Chee Shee, Ho, Gwo Fuang, Adlinda, Alip, Mohd Ibrahim, Abd Wahid, Matin Mellor, Abdullah, Foo, Yoke Ching, How, Soon Hin, Adel, Zaatar, Lam, Kai Seng, Leong, Kin-Wah, Low, JohnbSeng Hooi, Mastura, Md Yusof, Lee, Erica Chai Yong, Toh, Yok Yong, Liam, Chong Kin
• Format: Article
• Language: English
• Published: Springer Nature 2019
• Subjects: RC0254 Neoplasms. Tumors. Oncology (including Cancer)
• Online Access: http://ir.unimas.my/id/eprint/26798/1/Chai%2C%20Chee%20Shee.pdf; http://ir.unimas.my/id/eprint/26798/; https://bmccancer.biomedcentral.com/articles/10.1186/s12885-019-6107-1

Background: This study aimed to evaluate the efficacy, side-effects and resistance mechanisms of first-line afatinib in a real-world setting. Methods: This is a multicenter observational study of first-line afatinib in Malaysian patients with epidermal growth factor receptor (EGFR)-mutant advance...