New constraints between kinetic parameters explain the (un)identifiability of enzymatic rate constants

For an enzymatic reaction the rate constants in the assumed mechanism (k1,k_1, etc.)sometimes cannot. When identifiability problems occur, these are obscured by redundancy occurring among the steady-state parameters. This redundancy is only partly revealed by the known Haldane relations. We found th...

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Main Authors: Straathof, A. J. J., Heijnen, J. J.
格式: Article
語言:English
出版: John Wiley & Sons, Inc. 2008
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在線閱讀:http://dspace.unimap.edu.my/xmlui/handle/123456789/1503
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