Genetic and functional analysis of the proteolytic cleavage at the junction of the NS1 and NS2a proteins of murray valley encephalitis virus

Flaviviruses are a group of positive-strand RNA viruses of global significance. The flavivirus RNA genome encodes a single open reading frame that is directly translated into a single polyprotein and cleaved by host and virally encoded proteases prior to protein maturation. Hence, the proteolytic...

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Bibliographic Details
Main Author: Siti Nor Khadijah Addis
Format: Thesis
Language:English
Published: Australian national University 2012
Subjects:
Online Access:http://hdl.handle.net/123456789/1653
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