A bioanalytical method for quantification of telmisartan in rat plasma; development, validation and application to pharmacokinetic study

• Main Authors: AL-japairai, Khater Ahmed Saeed, Chatterjee, Bappaditya, Mahmood, Syed, Almurisi, Samah Hamed
• Format: Article
• Language: English
• Published: A and V publication 2021
• Subjects: Q Science (General)
• Online Access: http://umpir.ump.edu.my/id/eprint/25861/1/A%20Bioanalytical%20Method%20for%20Quantification%20of%20Telmisartan%20in%20rat%20Plasma%20Development%20Validation%20and%20Application%20to%20Pharmacokinetic%20Study.pdf; http://umpir.ump.edu.my/id/eprint/25861/; https: //doi.org/10.52711/0974-360X.2021.00379

The telmisartan was determined in a rat plasma using developed and validated a reversed-phase high performance liquid chromatographic (HPLC). The pre-treatment of the plasma sample involving liquid-liquid extraction using ethanol as the extracting solvent. The HPLC method validation has been shown a...