Identifying a Gene Knockout Strategy Using a Hybrid of Simple Constrained Artificial Bee Colony Algorithm and Flux Balance Analysis to Enhance the Production of Succinate and Lactate in Escherichia Coli

• Main Authors: Mei, Kie Hon, Mohd Saberi, Mohamad, Abdul Hakim, Mohamed Salleh, Yee, Wen Choon, Kauthar, Mohd Daud, Muhammad Akmal, Remli, Mohd Arfian, Ismail, Omatu, Sigeru, Sinnott, Richard O., Corchado, Juan Manuel
• Format: Article
• Language: English
• Published: Springer 2019
• Subjects: Q Science (General)
• Online Access: http://umpir.ump.edu.my/id/eprint/24904/1/Identifying%20a%20Gene%20Knockout%20Strategy%20Using%20a%20Hybrid%20of%20Simple.pdf; http://umpir.ump.edu.my/id/eprint/24904/; https://doi.org/10.1007/s12539-019-00324-z; https://doi.org/10.1007/s12539-019-00324-z

In recent years, metabolic engineering has gained central attention in numerous fields of science because of its capability to manipulate metabolic pathways in enhancing the expression of target phenotypes. Due to this, many computational approaches that perform genetic manipulation have been develo...