A hybrid of differential search algorithm and flux balance analysis to: Identify knockout strategies for in silico optimization of metabolites production

• Main Authors: Mohd. Daud, Kauthar, Zakaria, Zalmiyah, Ali Shah, Zuraini, Mohamad, Mohd. Saberi, Deris, Safaai, Omatu, Sigeru, Corchado, Juan Manuel
• Format: Article
• Language: English
• Published: International Center for Scientific Research and Studies 2018
• Subjects: QA75 Electronic computers. Computer science
• Online Access: http://eprints.utm.my/id/eprint/84598/1/KautharMohdDaud2018_AHybridofDifferentialSearchAlgorithmandFlux.pdf; http://eprints.utm.my/id/eprint/84598/; http://www.home.ijasca.com/article-in-press/volume-10-2018/vol-10-2/

An increasing demand of naturally producing metabolites has gained the attention of researchers to develop better algorithms for predicting the effects of reaction knockouts. With the success of genome sequencing, in silico metabolic engineering has aided the researchers in modifying the genome-scal...