Subditine, a new monoterpenoid indole Alkaloid from bark of Nauclea subdita (Korth.) Steud. Induces apoptosis in human prostate cancer cells

• Main Authors: Liew, S.Y., Looi, C.Y., Paydar, M., Cheah, F.K., Leong, K.H., Wong, W.F., Mustafa, Mohd Rais, Litaudon, M., Awang, Khalijah
• Format: Article
• Language: English
• Published: Public Library of Science 2014
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/9828/1/Liew-2014-Subditine%2C_a_New_Mon.pdf; http://eprints.um.edu.my/9828/

In this study, a new apoptotic monoterpenoid indole alkaloid, subditine (1), and four known compounds were isolated from the bark of Nauclea subdita. Complete 1H- and 13C- NMR data of the new compound were reported. The structures of isolated compounds were elucidated with various spectroscopic meth...