Structure, biological activity, and a biomimetic partial synthesis of the lirofolines, novel pentacylic indole alkaloids from Tabernaemontana

• Main Authors: Kam, T.S., Low, Y.Y., Lim, K.H., Choo, Y.M., Pang, H.S., Etoh, T., Hayashi, M., Komiyama, K.
• Format: Article
• Language: English
• Published: Elsevier 2010
• Subjects: QD Chemistry
• Online Access: http://eprints.um.edu.my/10396/1/Structure%2C_biological_activity%2C_and_a_biomimetic_partial_synthesis_of_the_lirofolines%2C_novel_pentacylic_indole_alkaloids_from_Tabernaemontana.pdf; http://eprints.um.edu.my/10396/

Two new pentacyclic indole alkaloids, lirofolines A and B, possessing a novel rearranged ibogan ring system, are obtained from two Malayan Tabernaemontana species ( Tabernaemontana corymbosa and Tabernaemontana divaricata) and the structures are established by analysis of the spectroscopic data. A...