Induction of apoptosis in melanoma A375 cells by a chloroform fraction of Centratherum anthelminticum (L.) seeds involves NF-kappaB, p53 and Bcl-2-controlled mitochondrial signaling pathways
Background: Centratherum anthelminticum (L.) Kuntze (scientific synonyms: Vernonia anthelmintica; black cumin) is one of the ingredients of an Ayurvedic preparation, called Kayakalpâ, commonly applied to treat skin disorders in India and Southeast Asia. Despite its well known anti-inflammatory prope...
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Main Authors: | Looi, C.Y., Moharram, B., Paydar, M., Wong, Y.L., Leong, K.H., Mohamad, K., Arya, A., Wong, W.F., Mustafa, Mohd Rais |
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Format: | Article |
Language: | English |
Published: |
BioMed Central
2013
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Subjects: | |
Online Access: | http://eprints.um.edu.my/9804/1/Induction_of_apoptosis_in_melanoma_A375.pdf http://eprints.um.edu.my/9804/ http://www.biomedcentral.com/1472-6882/13/166/ |
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