Boldine protects endothelial function in hyperglycemia-induced oxidative stress through an antioxidant mechanism

• Main Authors: Lau, Y.S., Tian, X.Y., Huang, Y., Murugan, D., Achike, F.I., Mustafa, Mohd Rais
• Format: Article
• Language: English
• Published: Elsevier 2012
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/8252/1/Boldine_protects_endothelial_function.pdf; http://eprints.um.edu.my/8252/; https://doi.org/10.1016/j.bcp.2012.11.010

Increased oxidative stress is involved in the pathogenesis and progression of diabetes. Antioxidants are therapeutically beneficial for oxidative stress-associated diseases. Boldine (s-2,9-dihydroxy-1,10-dimethoxyaporphine) is a major alkaloid present in the leaves and bark of the boldo tree (Peumus...