Structure-based identification of aporphines with selective 5-HT2A receptor-binding activity
Selective blockade of the serotonin 5-HT2A receptor is a useful therapeutic approach for a number of disorders, including schizophrenia, insomnia and ischaemic heart disease. A series of aporphines were docked into a homology model of the rat 5-HT2A receptor using AutoDock. Selected compounds with h...
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| Main Authors: | , , , , |
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| Format: | Article |
| Published: |
2013
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/8149/ http://onlinelibrary.wiley.com/doi/10.1111/cbdd.12069/abstract |
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