Association between polymorphism of genes encoding for 5-HT1A and 5-HT2A receptors and response to selective serotonin reuptake inhibitors in Malaysian patients with major depressive disorder

• Main Authors: Badamasi, Mohammed Ibrahim, Lye, Munn Sann, Ibrahim, Normala, Ling, King Hwa, Stanslas, Johnson
• Format: Article
• Language: English
• Published: Federation of American Societies for Experimental Biology 2017
• Online Access: http://psasir.upm.edu.my/id/eprint/60958/1/Association%20between%20polymorphism%20of%20genes%20encoding%20for%205-HT1A%20and%205-HT2A%20receptors%20and%20response%20to%20selective%20serotonin%20reuptake%20inhibitors%20in%20Malaysian%20patients%20with%20major%20depressive%20disorder.pdf; http://psasir.upm.edu.my/id/eprint/60958/; https://www.fasebj.org/doi/abs/10.1096/fasebj.31.1_supplement.1000.6

Inter-racial variations in genotype frequency have been implicated as a probable cause of the inconsistencies in pharmacogenetic studies of major depressive disorder (MDD). The aim of this study was to determine whether the polymorphisms of the serotonin 1A (5HT1A) 1019C>G and serotonin 2A (5HT2A...