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A physiological approach to renal clearance: From premature neonates to adults

AimsWe propose using glomerular filtration rate (GFR) as the physiological basis for distinguishing components of renal clearance.MethodsGentamicin, amikacin and vancomycin are thought to be predominantly excreted by the kidneys. A mixed-effects joint model of the pharmacokinetics of these drugs was...

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Bibliographic Details
Main Authors:	Holford, Nick, O'Hanlon, Conor J., Allegaert, Karel, Anderson, Brian, Falcao, Amilcar, Simon, Nicolas, Lo, Yoke-Lin, Thomson, Alison H., Sherwin, Catherine M., Jacqz-Aigrain, Evelyne, Llanos-Paez, Carolina, Hennig, Stefanie, Mockus, Linas, Kirkpatrick, Carl
Format:	Article
Published:	Wiley 2024
Subjects:	RM Therapeutics. Pharmacology RS Pharmacy and materia medica
Online Access:	http://eprints.um.edu.my/45774/ https://doi.org/10.1111/bcp.15978
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