Augmented renal clearance in critically ill patients with sepsis: prevalence, risk factors and outcome

• Main Authors: Abdul Rahim, Shahir Asraf, Md Ralib, Azrina, Mohamed, Abdul Hadi, Osman, Ariff, Mat Nor, Mohd Basri
• Format: Conference or Workshop Item
• Language: English
• Published: 2017
• Subjects: R Medicine (General)
• Online Access: http://irep.iium.edu.my/58146/1/58146_Augmented%20Renal%20Clearance.pdf; http://irep.iium.edu.my/58146/; http://www.iium.edu.my/medicine/news/medical-research-symposium-mrs-2017

Introduction: Augmented renal clearance (ARC) is a phenomenon where there is elevated renal clearance and defined by creatinine clearance > 130ml/min. ARC results in changes of the pharmacokinetic and pharmacodynamic of antimicrobial therapy being administered, which may result in its subtherapeu...