Matrix Metalloproteinases in Chemoresistance: Regulatory Roles, Molecular Interactions, and Potential Inhibitors

• Main Authors: Tune, Bernadette Xin Jie, Sim, Maw Shin, Poh, Chit Laa, Guad, Rhanye Mac, Woon, Choy Ker, Hazarika, Iswar, Das, Anju, Gopinath, Subash C. B., Rajan, Mariappan, Sekar, Mahendran, Subramaniyan, Vetriselvan, Fuloria, Neeraj Kumar, Fuloria, Shivkanya, Batumalaie, Kalaivani, Wu, Yuan Seng
• Format: Article
• Published: Hindawi Ltd 2022
• Subjects: R Medicine; RS Pharmacy and materia medica
• Online Access: http://eprints.um.edu.my/42209/

Cancer is one of the major causes of death worldwide. Its treatments usually fail when the tumor has become malignant and metastasized. Metastasis is a key source of cancer recurrence, which often leads to resistance towards chemotherapeutic agents. Hence, most cancer-related deaths are linked to th...