Antitubercular activity assessment of fluorinated chalcones, 2-aminopyridine-3-carbonitrile and 2-amino-4H-pyran-3-carbonitrile derivatives: In vitro, molecular docking and in-silico drug likeliness studies
A series of newer previously synthesized fluorinated chalcones and their 2-amino-pyridine3-carbonitrile and 2-amino-4H-pyran-3-carbonitrile derivatives were screened for their in vitro antitubercular activity and in silico methods. Compound 40 (MIC similar to 8 mu M) was the most potent among all 60...
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Main Authors: | Lagu, Surendra Babu, Yejella, Rajendra Prasad, Nissankararao, Srinath, Bhandare, Richie R., Golla, Venu Sampath, Lokesh, Bontha Venkata Subrahmanya, Rahman, M. Mukhlesur, Shaik, Afzal Basha |
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Format: | Article |
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Public Library of Science
2022
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Online Access: | http://eprints.um.edu.my/41493/ |
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