Design, characterization, in vitro antibacterial, antitubercular evaluation and structure–activity relationships of new hydrazinyl thiazolyl coumarin derivatives

• Main Authors: Samina KhanYusufzai, Hasnah Osman, Mohammad Shaheen Khan, Suriyati Mohamad, Othman Sulaiman, Thaigarajan Parumasivam, Azlan Jualang Gansau, Norhaniza Johansah, Noviany
• Format: Article
• Language: English
• Published: Springer US 2017
• Subjects: RC Internal medicine
• Online Access: https://eprints.ums.edu.my/id/eprint/19344/1/Design.pdf; https://eprints.ums.edu.my/id/eprint/19344/; https://doi.org/10.1007/s00044-017-1820-2

Herein, we describe the synthesis of 11new thiazolyl coumarin derivatives and evaluation of their potential role as antibacterial and antituberculosis agents. The structures of the synthesized compounds were established by extensive spectroscopic studies (Fourier transform infrared spectroscopy, 1H-...