Vaccine candidates generated by codon and codon pair deoptimization of enterovirus A71 protect against lethal challenge in mice
Enterovirus A71 (EV-A71) causes hand, foot and mouth disease (HFMD) in young children. It is associated with severe neurological complications and death. This study aims to develop a live-attenuated vaccine by codon deoptimization (CD) and codon-pair deoptimization (CPD) of EV-A71. CD is generated b...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Published: |
Elsevier Sci Ltd
2021
|
| Subjects: | |
| Online Access: | http://eprints.um.edu.my/28520/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|