LPS preconditioning attenuates apoptosis mechanism by inhibiting NF-kappa B and caspase-3 activity: TLR4 pre-activation in the signaling pathway of LPS-induced Neuroprotection

• Main Authors: Sangaran, Pushpa Gandi, Ibrahim, Zaridatul Aini, Chik, Zamri, Mohamed, Zahurin, Ahmadiani, Abolhassan
• Format: Article
• Published: Springer 2021
• Subjects: R Medicine (General)
• Online Access: http://eprints.um.edu.my/28002/

Neuroinflammation, an inflammatory response within the nervous system, has been shown to be implicated in the progression of various neurodegenerative diseases. Recent in vivo studies showed that lipopolysaccharide (LPS) preconditioning provides neuroprotection by activating Toll-like receptor 4 (TL...