Lipopolysaccharide pre-conditioning attenuates pro-inflammatory responses and promotes cytoprotective effect in differentiated PC12 cell lines via pre-activation of toll-like receptor-4 signaling pathway leading to the inhibition of caspase-3/nuclear factor-kappa appa B pathway

• Main Authors: Sangaran, Pushpa Gandi, Ibrahim, Zaridatul Aini, Chik, Zamri, Mohamed, Zahurin, Ahmadiani, Abolhassan
• Format: Article
• Published: Frontiers Media 2021
• Subjects: R Medicine (General)
• Online Access: http://eprints.um.edu.my/27999/

Lipopolysacharide (LPS) pre-conditioning (PC), has been shown to exert protective effects against cytotoxic effects. Therefore, we hypothesized, the tolerance produced by LPS PC will be resulted by the alterations and modifications in gene and protein expression. With reference to the results of MTT...