Protective effect of α-asarone against nicotine-induced seizures in mice, but not by its interaction with nicotinic acetylcholine receptors

Alpha-asarone is one of the bioactive phytochemicals present in the rhizomes of Acorus species and demonstrated its anticonvulsant activity in rodents. Alpha-asarone protected mice from the gamma-aminobutyric acid (GABA) type A receptor antagonist or N-methyl-D-aspartate (NMDA) receptor agonist-indu...

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Bibliographic Details
Main Authors: Chellian, Ranjithkumar, Pandy, Vijayapandi
Format: Article
Published: Elsevier 2018
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Online Access:http://eprints.um.edu.my/22253/
https://doi.org/10.1016/j.biopha.2018.09.137
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