PI3K/mTORC2 regulates TGF-β/Activin signalling by modulating Smad2/3 activity via linker phosphorylation
Crosstalk between the phosphatidylinositol 3-kinase (PI3K) and the transforming growth factor-β signalling pathways play an important role in regulating many cellular functions. However, the molecular mechanisms underpinning this crosstalk remain unclear. Here, we report that PI3K signalling antagon...
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Main Authors: | , , , , , , |
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Format: | Article |
Published: |
Nature Publishing Group
2015
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Online Access: | http://eprints.um.edu.my/19339/ http://dx.doi.org/10.1038/ncomms8212 |
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