FLT3 mutation and expression did not adversely affect clinical outcome of childhood acute leukaemiaua study of 531 Southeast Asian children by the Ma-Spore study group

• Main Authors: Leow, S., Kham, S.Kow-Yin, Ariffin, H., Quah, T.C., Yeoh, A.Eng-Juh
• Format: Article
• Published: John Wiley & Sons 2010
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/14707/

FMS-like tyrosine kinase 3 (FLT3) is critical for normal haematopoiesis and have been reported to be expressed in the majority of acute myeloid and lymphoid malignancies. We correlated the impact of FLT3 mutations and its expression with age, WHO 2008 classification and treatment outcome in 531 chil...