FLT3 and NPM1 mutations in patients with Myeloid neoplasms

• Main Authors: Mansoor, Mohammad Naem, Muhammad, Siti Aeshah @ Naznin, A. Talib, Norlelawati, Hamdan, Asmah Hanim, Abd. Aziz, Karimah Hanim, Ibrahim, Ismail, Ismail, Rusmawati
• Format: Article
• Language: English; English
• Published: Kulliyyah of Allied Health Sciences, International Islamic University Malaysia 2021
• Subjects: RB Pathology
• Online Access: http://irep.iium.edu.my/90519/1/abstract2%20KRD%202020.pdf; http://irep.iium.edu.my/90519/7/90519_FLT3%20and%20NPM1%20mutations%20in%20patients.pdf; http://irep.iium.edu.my/90519/; https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/555/521

Background: Acute myeloid leukemia (AML) and myeloproliferative neoplasms (MPN) are the most common entities of myeloid neoplasms. In AML, among the most frequent genetic alterations that carries both diagnostic and prognostic values are mutations in Nucleophosmin 1 (NPM1) and FMS-like tyrosine ki...