Cover Image

Bisnicalaterines B and C, atropisomeric bisindole alkaloids from hunteria zeylanica, showing vasorelaxant activity

Two new bisindole alkaloids, bisnicalaterines B and C (1 and 2) consisting of an eburnane and a corynanthe type of skeletons, were isolated from the bark of Hunteria zeylanica. Their absolute structures were determined by combination of NMR, CD, and computational methods, and each of them was shown...

Full description

Saved in:
Bibliographic Details
Main Authors: Hirasawa, Y., Hara, M., Nugroho, A.E., Sugai, M., Zaima, K., Kawahara, N., Goda, Y., Awang, K., Hadi, A.H.A., Litaudon, M., Morita, H.
Format: Article
Published: American Chemical Society 2010
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/13222/
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Two new bisindole alkaloids, bisnicalaterines B and C (1 and 2) consisting of an eburnane and a corynanthe type of skeletons, were isolated from the bark of Hunteria zeylanica. Their absolute structures were determined by combination of NMR, CD, and computational methods, and each of them was shown to be in an atropisomeric relationship. Bisnicalaterines B and C (1 and 2) showed potent vasorelaxant activity on isolated rat aorta.

Similar Items