Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii

• Main Authors: Hirasawa, Y., Shoji, T., Arai, T., Nugroho, A.E., Deguchi, J., Hosoya, T., Uchiyama, N., Goda, Y., Awang, K., Hadi, A.H.A., Shiro, M., Morita, H.
• Format: Article
• Published: Elsevier 2010
• Subjects: Q Science (General)
• Online Access: http://eprints.um.edu.my/14977/

A new bisindole alkaloid, bisleuconothine A(1) consisting of an eburnane-aspidosperma type skeleton, was isolated from the bark of Leuconotis griffithii. The structure including absolute stereochemistry was elucidated on the basis of 2D NMR data and X-ray analysis. Bisleuconothine A(1) showed cell g...