Carrageenophyte Kappaphycus malesianus Inhibits Microglia-Mediated Neuroinflammation via Suppression of AKT/NF-κB and ERK Signaling Pathways

• Main Authors: Lai, Nicole Jean Yean, Ngu, Ee Ling, Pang, Jun Rui, Wong, Kah Hui, Ardianto, Chrismawan, Long, Chiau Ming *, Lim, Siew Huah, Walvekar, Shweta Gangasa, Ayaz, Anwar, Yow, Yoon Yen *
• Format: Article
• Language: English
• Published: MDPI 2022
• Subjects: QK Botany; QP Physiology; RB Pathology
• Online Access: http://eprints.sunway.edu.my/3109/1/Long%20Chiau%20Ming_Carrageenophyte%20kappaphycus%20malesianus%20inhibits.pdf; http://eprints.sunway.edu.my/3109/; https://doi.org/10.3390/md20080534

Neuroinflammation is an inflammatory response in any part of the central nervous system triggered by the activation of microglia and astrocytes to produce proinflammatory cytokines in the brain. However, overproduction of proinflammatory cytokines further contributes to the development of neurodegen...