Flumazenil Pretreatment Reduces Mefenamic Acid-Induced Central Nervous System Toxicity in Mice
Background: Mefenamic acid (MFA), a common analgesic, causes central nervous system (CNS) toxicity at high doses with a proposed activity on the Gamma-aminobutyric acid (GABA) system. However, it remains unknown whether flumazenil (FMZ), a GABA type A receptor (GABAAR) antagonist, can reverse MFA to...
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Main Authors: | Jarrar, Qais, Ayoub, Rami, Jarrar, Yazun, Aburass, Hadeel, Goh, Khang Wen, Ardianto, Chrismawan, Long, Chiau Ming *, Moshawih, Said, Alfaqih, Hussain |
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Format: | Article |
Published: |
IMR Press
2023
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Online Access: | http://eprints.sunway.edu.my/2890/ https://www.imrpress.com/journal/JIN/22/4/10.31083/j.jin2204104 |
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