Role of leucine-rich pentatricopeptide repeat motif-containing protein (LRPPRC) for anti-apoptosis and tumourigenesis in cancers

• Main Authors: Tian, Tian, Ikeda, Jun-Ichiro, Wang, Yi, Mamat, Suhana, Luo, Wenjuan, Aozasa, Katsuyuki, Morii, Eiichi
• Format: Article
• Language: English
• Published: Elsevier Inc. 2012
• Subjects: QM Human anatomy
• Online Access: http://irep.iium.edu.my/29244/1/Role_of_leucine-rich_pentatricopeptide_repeat.pdf; http://irep.iium.edu.my/29244/; http://www.sciencedirect.com/science/article/pii/S0959804912000597#

Due to accelerated energy consumption, enhanced function of mitochondria in tumour cells compared to normal cells is prerequisite for tumour development. Leucine-rich pentatricopeptide repeat motif-containing protein (LRPPRC) regulates the expression of all mitochondrial DNA-encoded mRNAs, thus play...