Leveraging nitrogen occurrence in approved drugs to identify structural patterns

• Main Authors: Masand, Vijay H, Al-Hussain, Sami, Alzahrani, Abdullah Y., El-Sayed, Nahed N., Yeo, Chien Ing *, Tan, Yee Seng *, Zaki, Magdi E A
• Format: Article
• Published: Taylor and Francis Group 2024
• Subjects: QD Chemistry; RS Pharmacy and materia medica
• Online Access: http://eprints.sunway.edu.my/2561/; https://doi.org/10.1080/17460441.2023.2266990

Background The process of drug development and discovery is costly and slow. Although an understanding of molecular design principles and biochemical processes has progressed, it is essential to minimize synthesis-testing cycles. An effective approach is to analyze key heteroatoms, including oxygen...