3D-printed drugs: A fabrication of pharmaceuticals towards personalized medicine
Background: Three-dimensional (3D) printing fabricates a structure by depositing materials layer-by-layer to form an object. Drug personalization receives attention due to problems arising from drug treatments such as undesirable side effects and ineffective drug therapy among pediatric and ge...
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Association of Pharmaceutical Teachers of India (APTI)
2020
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Online Access: | http://irep.iium.edu.my/84266/1/IndJPhaEdRes-54-3s-s411.pdf http://irep.iium.edu.my/84266/ http://ijper.org/article/1257 |
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my.iium.irep.842662020-11-05T07:42:16Z http://irep.iium.edu.my/84266/ 3D-printed drugs: A fabrication of pharmaceuticals towards personalized medicine Haris @ Harith, Muhammad Salahuddin Mohd Azlan, Nur Hakimah Taher, Muhammad Mohd Rus, Shaiqah Chatterjee, Bappaditya RS Pharmacy and materia medica Background: Three-dimensional (3D) printing fabricates a structure by depositing materials layer-by-layer to form an object. Drug personalization receives attention due to problems arising from drug treatments such as undesirable side effects and ineffective drug therapy among pediatric and geriatric patients. Hypothesis: Conventional dosage form faces issues such as non-adherence to medication, ineffective treatment due to non-preferable dosage form and non-optimized drug release. Personalized 3D printing drugs offer personalized drug dosing, novel drug release profile and unique dosage form production. Results and Conclusion: Therefore, this review discussed the benefits of 3D-printed drugs and an overview of the standard 3D printer technology used in pharmaceuticals. This article aimed to review the current application of 3D-printed drugs in the personalization of drug dosing, the variation of drug release profile and fabrication of unique drug dosage form. Further research and experimentation of 3D-printed drugs are recommended as they will offer a significant aid in the customization of medicine. The potential utilization of 3D-printed drugs in optimizing effective and safe medication is undeniable. However, there are some challenges needed to be overcome, such as compatibility between chosen methods with materials used, difficulty to scale-up production, regulatory requirement as well as protection of individual rights issues. Association of Pharmaceutical Teachers of India (APTI) 2020-10 Article PeerReviewed application/pdf en http://irep.iium.edu.my/84266/1/IndJPhaEdRes-54-3s-s411.pdf Haris @ Harith, Muhammad Salahuddin and Mohd Azlan, Nur Hakimah and Taher, Muhammad and Mohd Rus, Shaiqah and Chatterjee, Bappaditya (2020) 3D-printed drugs: A fabrication of pharmaceuticals towards personalized medicine. Indian Journal of Pharmaceutical Education and Research, 54 (3s). S411-S422. ISSN 0019-5464 (In Press) http://ijper.org/article/1257 10.5530/ijper.54.3s.139 |
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RS Pharmacy and materia medica Haris @ Harith, Muhammad Salahuddin Mohd Azlan, Nur Hakimah Taher, Muhammad Mohd Rus, Shaiqah Chatterjee, Bappaditya 3D-printed drugs: A fabrication of pharmaceuticals towards personalized medicine |
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Background: Three-dimensional (3D) printing fabricates a structure by depositing
materials layer-by-layer to form an object. Drug personalization receives attention due to
problems arising from drug treatments such as undesirable side effects and ineffective
drug therapy among pediatric and geriatric patients. Hypothesis: Conventional dosage
form faces issues such as non-adherence to medication, ineffective treatment due to
non-preferable dosage form and non-optimized drug release. Personalized 3D printing
drugs offer personalized drug dosing, novel drug release profile and unique dosage
form production. Results and Conclusion: Therefore, this review discussed the benefits
of 3D-printed drugs and an overview of the standard 3D printer technology used in
pharmaceuticals. This article aimed to review the current application of 3D-printed drugs
in the personalization of drug dosing, the variation of drug release profile and fabrication
of unique drug dosage form. Further research and experimentation of 3D-printed drugs
are recommended as they will offer a significant aid in the customization of medicine.
The potential utilization of 3D-printed drugs in optimizing effective and safe medication
is undeniable. However, there are some challenges needed to be overcome, such as
compatibility between chosen methods with materials used, difficulty to scale-up
production, regulatory requirement as well as protection of individual rights issues. |
format |
Article |
author |
Haris @ Harith, Muhammad Salahuddin Mohd Azlan, Nur Hakimah Taher, Muhammad Mohd Rus, Shaiqah Chatterjee, Bappaditya |
author_facet |
Haris @ Harith, Muhammad Salahuddin Mohd Azlan, Nur Hakimah Taher, Muhammad Mohd Rus, Shaiqah Chatterjee, Bappaditya |
author_sort |
Haris @ Harith, Muhammad Salahuddin |
title |
3D-printed drugs: A fabrication of pharmaceuticals towards personalized medicine |
title_short |
3D-printed drugs: A fabrication of pharmaceuticals towards personalized medicine |
title_full |
3D-printed drugs: A fabrication of pharmaceuticals towards personalized medicine |
title_fullStr |
3D-printed drugs: A fabrication of pharmaceuticals towards personalized medicine |
title_full_unstemmed |
3D-printed drugs: A fabrication of pharmaceuticals towards personalized medicine |
title_sort |
3d-printed drugs: a fabrication of pharmaceuticals towards personalized medicine |
publisher |
Association of Pharmaceutical Teachers of India (APTI) |
publishDate |
2020 |
url |
http://irep.iium.edu.my/84266/1/IndJPhaEdRes-54-3s-s411.pdf http://irep.iium.edu.my/84266/ http://ijper.org/article/1257 |
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