3D-printed drugs: A fabrication of pharmaceuticals towards personalized medicine
Background: Three-dimensional (3D) printing fabricates a structure by depositing materials layer-by-layer to form an object. Drug personalization receives attention due to problems arising from drug treatments such as undesirable side effects and ineffective drug therapy among pediatric and ge...
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Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Association of Pharmaceutical Teachers of India (APTI)
2020
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Subjects: | |
Online Access: | http://irep.iium.edu.my/84266/1/IndJPhaEdRes-54-3s-s411.pdf http://irep.iium.edu.my/84266/ http://ijper.org/article/1257 |
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Summary: | Background: Three-dimensional (3D) printing fabricates a structure by depositing
materials layer-by-layer to form an object. Drug personalization receives attention due to
problems arising from drug treatments such as undesirable side effects and ineffective
drug therapy among pediatric and geriatric patients. Hypothesis: Conventional dosage
form faces issues such as non-adherence to medication, ineffective treatment due to
non-preferable dosage form and non-optimized drug release. Personalized 3D printing
drugs offer personalized drug dosing, novel drug release profile and unique dosage
form production. Results and Conclusion: Therefore, this review discussed the benefits
of 3D-printed drugs and an overview of the standard 3D printer technology used in
pharmaceuticals. This article aimed to review the current application of 3D-printed drugs
in the personalization of drug dosing, the variation of drug release profile and fabrication
of unique drug dosage form. Further research and experimentation of 3D-printed drugs
are recommended as they will offer a significant aid in the customization of medicine.
The potential utilization of 3D-printed drugs in optimizing effective and safe medication
is undeniable. However, there are some challenges needed to be overcome, such as
compatibility between chosen methods with materials used, difficulty to scale-up
production, regulatory requirement as well as protection of individual rights issues. |
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