Bioactive compounds from Aspergillus niger extract enhance the antioxidant activity and prevent the genotoxicity in aflatoxin B1-treated rats

• Main Authors: Abdel-Wahhab, Mosaad Attia, El-Nekeety, Aziza Abdel Salam, Hathout, Amal S., Salman, Asmaa S., Abdel-Aziem, Sekena H., Sabry, Bassem A., Hassan, Nabila Salah, Abdel-Aziz, Mohammed S., Aly, Soher E., Jaswir, Irwandi
• Format: Article
• Language: English; English
• Published: Elsevier Ltd 2020
• Subjects: QH301 Biology; TP Chemical technology; TP368 Food processing and manufacture
• Online Access: http://irep.iium.edu.my/82209/2/82209_Bioactive%20compounds%20from%20Aspergillus%20niger%20extract_FULL%20TEXT.pdf; http://irep.iium.edu.my/82209/1/82209_Bioactive%20compounds%20from%20Aspergillus%20niger%20extract_SCOPUS.pdf; http://irep.iium.edu.my/82209/; https://www.sciencedirect.com/science/article/abs/pii/S004101012030221X

This study aimed to identify the bioactive compounds of the ethyl acetate extract of Aspergillus niger SH2-EGY using GC-MS and to evaluate their protective role against aflatoxin B1 (AFB1)-induced oxidative stress, genotoxicity and cytotoxicity in rats. Six groups of male Sprague-Dawley rats were tr...