In-silico identification of potential protein arginine deiminase IV (PAD4) inhibitors = Pengenalpastian in-silico yang berpotensi sebagai perencat protin arginina deiminase IV (PAD4))

• Main Authors: Ibrahim, Zalikha, Tejo, Bimo Ario, Mohammad Latif, Muhammad Alif, Karjiban, Roghayeh Abedi, Salleh, Abu Bakar, Abdul Rahman, Mohd Basyaruddin
• Format: Article
• Language: English; English
• Published: Faculty of Science and Technology, Universiti Kebangsaan Malaysia 2016
• Subjects: QD Chemistry
• Online Access: http://irep.iium.edu.my/57350/1/Zalikha_20_6_5_SKAM2015.pdf; http://irep.iium.edu.my/57350/2/57350-In-Silico%20identification%20of%20potential%20protein_SCOPUS.pdf; http://irep.iium.edu.my/57350/; http://www.ukm.my/mjas/v20_n6/pdf/Zalikha_20_6_5.pdf

Protein Arginine Deiminase IV (PAD4) is a promising target for treating rheumatoid arthritis. Here, an in-silico screening was performed using PAD4 crystal structure against National Cancer Institute Diversity Set III compounds. Results obtained from the docking studies showed that the compounds hav...