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Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia

Protein phosphatase inhibition assay (PPIA), Neuroblastoma cell-based assay (Neuro-2a CBA)and LC-MS/MS analysis revealed for the first time the production of okadaic acid (OA) by a Prorocentrum rhathymum strain. Low amounts of OA were detected by LC-MS/MS analysis.Inhibition of PP2A activity and a...

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Main Authors: Caillaud, A, de la Iglesia, P, Campa` s, M, Elandaloussi, L, Ferna´ndez, M, Mohammad Noor, Normawaty, Andree, K, Dioge`ne, J
Format: Article
Language:English
Published: Elsevier 2010
Subjects:
QD Chemistry
SH Aquaculture. Fisheries. Angling
Online Access:http://irep.iium.edu.my/2638/1/P-rhathymum_-Toxicon.pdf
http://irep.iium.edu.my/2638/
http://www.elsevier.com/locate/toxicon
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spelling my.iium.irep.26382011-12-20T08:44:29Z http://irep.iium.edu.my/2638/ Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia Caillaud, A de la Iglesia, P Campa` s, M Elandaloussi, L Ferna´ndez, M Mohammad Noor, Normawaty Andree, K Dioge`ne, J QD Chemistry SH Aquaculture. Fisheries. Angling Protein phosphatase inhibition assay (PPIA), Neuroblastoma cell-based assay (Neuro-2a CBA)and LC-MS/MS analysis revealed for the first time the production of okadaic acid (OA) by a Prorocentrum rhathymum strain. Low amounts of OA were detected by LC-MS/MS analysis.Inhibition of PP2A activity and a weak toxicity to the Neuro-2a CBA were also observed. Elsevier 2010 Article REM application/pdf en http://irep.iium.edu.my/2638/1/P-rhathymum_-Toxicon.pdf Caillaud, A and de la Iglesia, P and Campa` s, M and Elandaloussi, L and Ferna´ndez, M and Mohammad Noor, Normawaty and Andree, K and Dioge`ne, J (2010) Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia. Toxicon, 55. pp. 633-637. ISSN 0041-0101 http://www.elsevier.com/locate/toxicon
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic QD Chemistry
SH Aquaculture. Fisheries. Angling
spellingShingle QD Chemistry
SH Aquaculture. Fisheries. Angling
Caillaud, A
de la Iglesia, P
Campa` s, M
Elandaloussi, L
Ferna´ndez, M
Mohammad Noor, Normawaty
Andree, K
Dioge`ne, J
Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia
description Protein phosphatase inhibition assay (PPIA), Neuroblastoma cell-based assay (Neuro-2a CBA)and LC-MS/MS analysis revealed for the first time the production of okadaic acid (OA) by a Prorocentrum rhathymum strain. Low amounts of OA were detected by LC-MS/MS analysis.Inhibition of PP2A activity and a weak toxicity to the Neuro-2a CBA were also observed.
format Article
author Caillaud, A
de la Iglesia, P
Campa` s, M
Elandaloussi, L
Ferna´ndez, M
Mohammad Noor, Normawaty
Andree, K
Dioge`ne, J
author_facet Caillaud, A
de la Iglesia, P
Campa` s, M
Elandaloussi, L
Ferna´ndez, M
Mohammad Noor, Normawaty
Andree, K
Dioge`ne, J
author_sort Caillaud, A
title Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia
title_short Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia
title_full Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia
title_fullStr Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia
title_full_unstemmed Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia
title_sort evidence of okadaic acid production in a cultured strain of the marine dinoflagellate prorocentrum rhathymum from malaysia
publisher Elsevier
publishDate 2010
url http://irep.iium.edu.my/2638/1/P-rhathymum_-Toxicon.pdf
http://irep.iium.edu.my/2638/
http://www.elsevier.com/locate/toxicon
_version_ 1643604999474774016
score 13.214268

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