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Integrated metabolomic and transcriptomic analyses of the synergistic effect of polymyxin–rifampicin combination against Pseudomonas aeruginosa

Background: Understanding the mechanism of antimicrobial action is critical for improving antibiotic therapy. For the first time, we integrated correlative metabolomics and transcriptomics of Pseudomonas aeruginosa to elucidate the mechanism of synergistic killing of polymyxin–rifampicin combination...

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Bibliographic Details
Main Authors: Mahamad Maifiah, Mohd Hafidz, Zhu, Yan, T. Tsuji, Brian, J. Creek, Darren, Velkov, Tony, Li, Jian
Format: Article
Language:English
Published: Springer Nature 2022
Subjects:
QD Chemistry
QR Microbiology
RM300 Drugs and their action
Online Access:http://irep.iium.edu.my/100941/7/100941_Integrated%20metabolomic%20and%20transcriptomic%20analyses.pdf
http://irep.iium.edu.my/100941/
https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929-022-00874-3
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http://irep.iium.edu.my/100941/7/100941_Integrated%20metabolomic%20and%20transcriptomic%20analyses.pdf
http://irep.iium.edu.my/100941/
https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929-022-00874-3

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