Synthesis, Isolation, Identification and Characterization of a Drug-Excipient Interaction Degradation Impurity in Pramipexole by HPLC, LC/MS and NMR
A drug-excipient interaction impurity associated with the degradation process of pramipexole was isolated. The impurity was detected during the stability study of pramipexole extended-release tablets. It was found at a relative retention time of 0.88 with respect to pramipexole, using the pramipexol...
Saved in:
Main Authors: | Al-Rifai, N., Alshishani, A., Saad, B., Rasras, A., Zahra, J., Madieh, S., Darras, F. |
---|---|
Format: | Article |
Published: |
2023
|
Online Access: | http://scholars.utp.edu.my/id/eprint/34342/ https://www.scopus.com/inward/record.uri?eid=2-s2.0-85146763954&doi=10.3390%2fseparations10010007&partnerID=40&md5=4c68c7807a2c5a7a08f2e0776a7a8d8c |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Development of a method for quantification of two genotoxic impurities in lurasidone using LC-MS/MS
by: Venu, M., et al.
Published: (2019) -
Development of a method for quantification of two genotoxic impurities in lurasidone using LC-MS/MS
by: Venu, Manthrapudi, et al.
Published: (2019) -
Chemical Compound Characterizations of Patchouli Leaf Extract via GC-MS, LC-QTOF-MS, FTIR, and 1H NMR
by: Sundarajan, Sangeethavani, et al.
Published: (2019) -
Analysis of drug impurities
by: Smith, Richard J., et al.
Published: (2012) -
Trace level quantification of 1-(3-chloropropyl)-4-(3-chlorophenyl)piperazine HCl genotoxic impurity in trazodone using LC–MS/MS
by: Venugopal, Nandigam, et al.
Published: (2019)